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Doctor's Best NAC Detox Regulators
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.9
USERS' SCORE
Excellent
Based on 99 Reviews
9
Supplement Facts
Serving Size: 1 Veggie Capsule
Amount Per Serving
%DV
Selenium (from SelenoExcell® High Selenium Yeast) (Saccharomyces cerevisiae)
50 mcg
90%
Molybdenum (from molybdenum glycinate chelate)
50 mcg
110%
N-Acetylcysteine (NAC)
600 mg

Top Medical Research Studies

9.5
Selenium nanoparticles reduce liver toxicity
Chitosan-encapsulated selenium nanoparticles alleviate CCl induced hepatotoxicity through synergistically modulating NF-κB and Nrf2 signaling pathways and regulating Bcl-2 and Caspase-3 expression: A comprehensive study with multiple regression analysis.
High relevance to liver toxicity
We investigated how selenium nanoparticles (Se-NPs) and chitosan-encapsulated selenium nanoparticles (Se-CS-NPs) can mitigate liver toxicity induced by carbon tetrachloride (CCl) in rats. In our study, eighty rats were divided into eight groups, including placebo and control.

The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
Read More
8
Potential selenium benefits on liver
Selenium nanoparticles alleviates cadmium induced hepatotoxicity by inhibiting ferroptosis and oxidative stress in vivo and in vitro.
High relevance for hepatotoxicity research
We examined how selenium nanoparticles might help combat liver damage caused by cadmium, a dangerous environmental toxin. By studying both animal models and liver cells, we found that these nanoparticles could reduce cell injuries linked to a damaging process called ferroptosis.

Our findings indicated that achieving this protective effect involves enhancing certain liver enzyme activities and altering several protein levels associated with oxidative stress. Overall, while selenium shows promise in mitigating liver damage, particularly against cadmium toxicity, further research could better clarify its mechanisms and potential benefits.
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9
Selenium aids in liver protection
Selenium Attenuates Ethanol-induced Hepatocellular Injury by Regulating Ferroptosis and Apoptosis.
Significant findings on liver health
We explored the potential of selenium in addressing liver damage caused by alcohol. The study employed both in vitro and in vivo methods to assess how selenium affects liver cells exposed to ethanol.

Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.

Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
Read More

Most Useful Reviews

9.5
Enhances liver detoxification
N-acetylcysteine is an excellent antioxidant that helps restore intestinal walls and removes mucus from the respiratory tract while aiding liver detoxification from toxins and heavy metals. I take it for two months on an empty stomach, as advised by my nutritionist. Our health is in our hands!
Read More
9.5
Helps relieve toxins
Acetylcysteine truly is a superfood! It boosts glutathione production in the liver, aids detoxification, and helps remove toxins, including alcohol by-products. This product excellently supports all liver functions. I highly recommend it for liver health at an affordable price!
Read More
9.5
NAC for liver protection
N-acetyl cysteine (NAC) is an excellent liver protector and an integral part of standard care for acetaminophen overdose. It's also effective against various health threats, including acute liver failure, making it essential for anyone concerned about liver health.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.9
  • All Researches
9.5
Selenium nanoparticles reduce liver toxicity
Chitosan-encapsulated selenium nanoparticles alleviate CCl induced hepatotoxicity through synergistically modulating NF-κB and Nrf2 signaling pathways and regulating Bcl-2 and Caspase-3 expression: A comprehensive study with multiple regression analysis.
High relevance to liver toxicity
We investigated how selenium nanoparticles (Se-NPs) and chitosan-encapsulated selenium nanoparticles (Se-CS-NPs) can mitigate liver toxicity induced by carbon tetrachloride (CCl) in rats. In our study, eighty rats were divided into eight groups, including placebo and control.

The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
Read More
9
Selenium and CoQ improve liver health
Coenzyme Q and Selenium Co-Supplementation Alleviate Methionine Choline-Deficient Diet-Induced Metabolic Dysfunction-Associated Steatohepatitis in Mice.
High relevance for liver treatment
We aimed to investigate the role of selenium and coenzyme Q in addressing liver damage caused by a methionine choline-deficient diet in mice. Over four weeks, mice receiving the combination treatment showed significant reductions in liver inflammation, fibrosis, and oxidative stress.

The results suggested that this combined supplementation might hold therapeutic potential against metabolic dysfunction-associated liver injury. While our findings are promising, they are based on an animal model, and further research is necessary to explore their implications for human liver disease.
Read More
9
Selenium enhances liver health
Glutathione and Selenium Supplementation Attenuates Liver Injury in Diethylnitrosamine-Induced Hepatocarcinogenic Mice by Enhancing Glutathione-Related Antioxidant Capacities.
High relevance to liver research
We set out to investigate if selenium, along with glutathione, can help reduce liver injury caused by a cancer-inducing substance in mice. Over 20 weeks, we divided male mice into different groups, some receiving selenium and others just glutathione, while monitoring their liver function.

Our findings revealed that both supplements significantly improved liver conditions and antioxidant levels. Interestingly, adding selenium to glutathione treatment worked even better, enhancing the liver’s ability to handle oxidative stress. Overall, selenium appears to be a promising ally in supporting liver health and reducing injury.
Read More
9
Selenium aids in liver protection
Selenium Attenuates Ethanol-induced Hepatocellular Injury by Regulating Ferroptosis and Apoptosis.
Significant findings on liver health
We explored the potential of selenium in addressing liver damage caused by alcohol. The study employed both in vitro and in vivo methods to assess how selenium affects liver cells exposed to ethanol.

Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.

Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
Read More
8
Saccharomyces cerevisiae aids liver health
Engineered S. cerevisiae-pYD1-ScFv-AFB1 mitigates aflatoxin B1 toxicity via bio-binding and intestinal microenvironment repair.
Effective yeast treatment evaluated
We explored the potential of an engineered yeast, S. cerevisiae-pYD1-ScFv-AFB1, in addressing liver damage caused by aflatoxin B1 (AFB1), a known cancer risk factor. Using a mouse model, we treated subjects with this specialized yeast for four weeks.

The results showed that the engineered yeast significantly reduced inflammation and cellular damage in the liver, and improved antioxidant capacity. Additionally, it helped repair the intestinal barrier disrupted by AFB1. These findings suggest it may offer a new way to combat AFB1 toxicity.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 99 Reviews
9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Enhances liver detoxification
N-acetylcysteine is an excellent antioxidant that helps restore intestinal walls and removes mucus from the respiratory tract while aiding liver detoxification from toxins and heavy metals. I take it for two months on an empty stomach, as advised by my nutritionist. Our health is in our hands!
Read More
9.5
Helps relieve toxins
Acetylcysteine truly is a superfood! It boosts glutathione production in the liver, aids detoxification, and helps remove toxins, including alcohol by-products. This product excellently supports all liver functions. I highly recommend it for liver health at an affordable price!
9.5
NAC for liver protection
N-acetyl cysteine (NAC) is an excellent liver protector and an integral part of standard care for acetaminophen overdose. It's also effective against various health threats, including acute liver failure, making it essential for anyone concerned about liver health.
10
Life-changing detox
I was exhausted and recommend this product for liver detox. After trying various remedies with no success, this product transformed my life. After completing the box, my tests showed that everything was fine. The bile is excreted, and the liver fat is gone. Thank you.
8.8
Efficient liver maintenance
I take NAC detox annually for liver health. The package has just enough for the course, and given my genetic predisposition to Gilbert's syndrome, this supplement is crucial for monitoring and maintaining my liver health. Under my nutritionist's guidance, I've significantly improved my health, confirmed by tests and my general well-being.
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